치아 회분말과 연석고를 이용한 초기 골치유시 알긴산의 효과
Effect of Alginate on Early Bone Healing after Implantation of Particulate Dentin and Plaster of Paris Mixture
소속 상세정보
조경안/Cho KA
김수관/임성철/김생곤/Kim SG/Lim SC/Kim SG
KMID : 0360120050270030218
Abstract
In this study, we expected that alginate would act as an antioxidant, owing to its antimicrobial and anti-parasitic effects and to clinical results in arthritic patients, and would thereby reduce the number of cytotoxic free radicals and the inflammatory reaction in response to grafting with a particulate dentin and plaster of Paris mixture, resulting in effective bone healing. In this study, the differences within groups at 4 and 8 weeks were not significant (p > 0.05), nor were the differences between the two experimental groups at 4 and 8 weeks. In comparison with the control group, however, both experimental groups showed superior new bone formation. Although the difference between the two experimental groups was not statistically significant, a tendency for superior new bone formation was detected with the combination of particulate dentin, plaster of Paris, and alginate. Furthermore, more fusion of woven bone and bony trabeculae formation occurred in this group, suggesting that oligosaccharides play a role in the formation and maturation of new bone. In conclusion, the treatment of bone defects by grafting with a mixture of particulate dentin and plaster of Paris alone or with alginate significantly improved the formation of new bone, both quantitatively and qualitatively. The oligosaccharide treatment appeared to improve the formation of new bone quantitatively and qualitatively.
키워드
원문 및 링크아웃 정보
등재저널 정보